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<<   作成日時 : 2007/12/17 20:21   >>

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ハチミツは子どもの咳の特効薬
 スプーン一杯のハチミツは最も一般的な市販の咳止めよりも効果的で、安全に子供の咳を静める。
 2才から18才までの105人の上気道感染による咳の子どもを3グループに分けて、効果を調べた。治療しない群、ハチミツ香料入りデキストロメトルファン群、ハチミツ群にわけ、咳の頻度と程度、子どもと両親の睡眠への影響を調べたところ、どの指標もハチミツの効果が優れていた。ハチミツは確立した酸化防止と抗菌効果を持ち、含まれるあらゆる種類の甘い物質が気道の粘液を溶かし、のどをなだめることに役立っている可能性がある。
 10月にFDAは、6才以下の子どもにはデキストロメトルファンを含め市販の風邪薬の販売禁止を推奨した。
 1才以上の子どもの咳に対して代替療法としてハチミツが考慮されるべきだが、1才未満の場合はまれにボツリヌス中毒をおこす恐れがあるために推奨されない
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Nostrums: Tame a Child’s Cough With a Touch of Honey
http://www.nytimes.com/2007/12/11/health/research/11nost.html?_r=1&ref=health&oref=slogin
By NICHOLAS BAKALAR
Published: December 11, 2007

A spoonful of honey might quiet a child’s cough more effectively and safely than the most common over-the-counter cough medicine.

画像Researchers tested 105 children 2 to 18 with coughs from upper-respiratory infections, dividing them randomly into three groups. One received no treatment. The others received a remedy, but the researchers, parents and children did not know which it was: one or two teaspoons of buckwheat honey, depending on age, or an age-appropriate dose of honey-flavored dextromethorphan. The study was supported by a grant from the National Honey Board, an industry-backed agency of the Department of Agriculture.

Using questionnaires filled out by the parents, the scientists measured cough frequency and severity, and the effect on the children’s and parents’ sleep. By all measures, honey provided the greatest relief.

Honey, the authors wrote in the December issue of The Archives of Pediatric and Adolescent Medicine, has well-established antioxidant and antimicrobial effects, and it might be that sweet substances of any kind help dissolve mucus in the airways and soothe the back of the throat.

In October, a Food and Drug Administration advisory panel recommended a ban on over-the-counter cold medicine, including some brands containing dextromethorphan, intended for children under age 6.

Dr. Ian M. Paul, the lead author and an associate professor of pediatrics at Penn State, said that parents should consider honey “as an alternative to cough medicine for children over age 1.” In rare cases, honey can cause infantile botulism in children under 1.

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Effect of Honey, Dextromethorphan, and No Treatment on Nocturnal Cough and Sleep Quality for Coughing Children and Their Parents

Ian M. Paul, MD, MSc; Jessica Beiler, MPH; Amyee McMonagle, RN; Michele L. Shaffer, PhD; Laura Duda, MD; Cheston M. Berlin Jr, MD

Arch Pediatr Adolesc Med. 2007;161(12):1140-1146.

Objectives To compare the effects of a single nocturnal dose of buckwheat honey or honey-flavored dextromethorphan (DM) with no treatment on nocturnal cough and sleep difficulty associated with childhood upper respiratory tract infections.

Design A survey was administered to parents on 2 consecutive days, first on the day of presentation when no medication had been given the prior evening and then the next day when honey, honey-flavored DM, or no treatment had been given prior to bedtime according to a partially double-blinded randomization scheme.

Setting A single, outpatient, general pediatric practice.

Participants One hundred five children aged 2 to 18 years with upper respiratory tract infections, nocturnal symptoms, and illness duration of 7 days or less.

Intervention A single dose of buckwheat honey, honey-flavored DM, or no treatment administered 30 minutes prior to bedtime.

Main Outcome Measures Cough frequency, cough severity, bothersome nature of cough, and child and parent sleep quality.

Results Significant differences in symptom improvement were detected between treatment groups, with honey consistently scoring the best and no treatment scoring the worst. In paired comparisons, honey was significantly superior to no treatment for cough frequency and the combined score, but DM was not better than no treatment for any outcome. Comparison of honey with DM revealed no significant differences.

Conclusions In a comparison of honey, DM, and no treatment, parents rated honey most favorably for symptomatic relief of their child's nocturnal cough and sleep difficulty due to upper respiratory tract infection. Honey may be a preferable treatment for the cough and sleep difficulty associated with childhood upper respiratory tract infection.

Trial Registration clinicaltrials.gov Identifier: NCT00127686.


Author Affiliations: Departments of Pediatrics (Drs Paul, Duda, and Berlin and Mss Beiler and McMonagle) and Public Health Sciences (Drs Paul and Shaffer), College of Medicine, Pennsylvania State University, Hershey.

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