医師の一分

アクセスカウンタ

zoom RSS 汎用インフルエンザワクチン開発

<<   作成日時 : 2008/01/07 22:55   >>

ブログ気持玉 0 / トラックバック 0 / コメント 0

 全てのタイプのインフルエンザから一生身を守れるワクチンACAM-FLU-Aが開発され、臨床試験で良い結果が出ている。
 英国で毎年4,000人がインフルエンザで死亡しており、世界中では50万から100万人が毎年死亡している
 現在のワクチンは haemagglutinin と neuraminidase というウイルス表面の2つの蛋白質に対する免疫力をつけるものであるが、これらの蛋白質は変異し続けるので、新たなワクチンを作り続ける必要が出てくる。
 Acambis vaccine はA型インフルエンザの表面の変異しないM2蛋白にたいする免疫力をつくる。さらにもっと大きな集団でのワクチン接種テストが必要とされる。
----------------------------------------
Last Updated: Friday, 4 January 2008, 10:18 GMT
http://news.bbc.co.uk/2/hi/health/7171118.stm
Universal flu jab works in people

画像flu
The vaccine is designed to protect against all flu strains

A single jab that could give lifelong protection against all types of flu has produced promising results in human trials.
The vaccine, made by Acambis, should protect against all strains of influenza A - the cause of pandemics.
Currently, winter flu jabs have to be regularly redesigned because the flu virus keeps changing.
The new vaccine would overcome this and could be stockpiled in advance of a bird flu outbreak, say experts.
Promising results
Each year winter flu kills around 4,000 people in the UK.
Globally, between 500,000 and one million people die each year from influenza.
But a pandemic of the human form of bird flu, which experts believe is inevitable, could kill as many as 50m people worldwide.
The US trials show that the jab is safe and it works fast to make the body immune against flu.

It could be stockpiled in advance of a pandemic
Dr Michael Watson of Acambis

Nine out of 10 of those who had two doses of the jab ACAM-FLU-A developed antibodies against flu virus.
Scientists at Acambis are now working to perfect the formulation before doing larger human trials.
Dr Michael Watson of Acambis said: "As a universal vaccine, ACAM-FLU-A can potentially overcome many of the drawbacks of existing influenza vaccines.
"It can be manufactured at any time of the year, and could be stockpiled in advance of a pandemic or potentially used routinely to ensure population protection against future pandemics."
Unique action
Current flu vaccines work by giving immunity to two proteins called haemagglutinin and neuraminidase, which are found on the surface of flu viruses.
However, these proteins keep mutating which means doctors have to keep making new vaccine to keep up.

The Acambis vaccine hones in on a different protein, called M2, which is found on the surface of all A-strains of flu and does not mutate.

Professor Ian Jones, a University of Reading virologist, said the jab could end the scramble to produce a new winter jab each year.

But he said it would still be some years before it was widely available for patients.

"Larger trials and tests on a wider range of viruses will be needed before the full potential for pandemic protection can be assured," he said.

テーマ

関連テーマ 一覧


月別リンク

ブログ気持玉

クリックして気持ちを伝えよう!
ログインしてクリックすれば、自分のブログへのリンクが付きます。
→ログインへ

トラックバック(0件)

タイトル (本文) ブログ名/日時

トラックバック用URL help


自分のブログにトラックバック記事作成(会員用) help

タイトル
本 文

コメント(0件)

内 容 ニックネーム/日時

コメントする help

ニックネーム
本 文
汎用インフルエンザワクチン開発 医師の一分/BIGLOBEウェブリブログ
文字サイズ:       閉じる