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処方薬乱用による死亡が増加/米国医療事情 薬物乱用
 45-64才の女性にとってショッキングなデータである。1999-2005年で毒物死が230%増加した。処方薬の乱用による死亡が第1位であり、第2位の違法薬物をはるかリードしている。米国人の約20%は医学的ではない理由で処方薬を飲んでいる。自分に処方されたものではなく、多くは友人や家族の好意でもらったものである。薬剤間の相互作用は時に重症で致命的となる。メタドン、ヒドロコドン、オキシコドンのようなよく使われる鎮痛薬を処方する医師を“doctor shop”するという気がかりな傾向が出ている。更に違法に売買されている。ウェストバージニアは処方薬の依存が知られる地域であり、こうした薬剤の550%もの増加が見られた。
 こうした傾向に戦うために医師が患者の処方薬物依存を見つける手助けとなるようなガイドラインの改善が必要とされる。
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医師や看護士によるプロポフォール乱用の増加/米国医療事情 薬物中毒
http://kurie.at.webry.info/200909/article_14.html
マイケル・ジャクソンの死因はプロポフォール/米国 薬物中毒 ディプリバン
http://kurie.at.webry.info/200907/article_39.html
ヒース・レジャー 死亡原因は多剤薬物中毒
http://kurie.at.webry.info/200802/article_20.html
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Poisoning Deaths on the Rise
How dangerous are your prescription drugs?
Posted by Jeri_at_Health on Tuesday, September 8, 2009 12:00 PM
http://health.msn.com/blogs/daily-dose-post.aspx?post=1258599

If you're a woman between 45 and 64 years of age, you'll be shocked to hear this stat. Between 1999 and 2005, the rate of poisoning deaths rose by 230 percent for this demographic. Poisoning?

Look to the medicine cabinet for answers. Dr. Susan P. Baker, the co-author of a recent study released by the Johns Hopkins Bloomberg School of Public Health's Center for Injury Research and Policy indicates the increase in poisoning is primarily due to the abuse of prescription drugs. Data from the Centers for Disease Control and Prevention show that prescription drugs have taken the lead in fatal drug overdoses, leaving illegal drugs in second place.

While most individuals take prescriptions for the purpose intended, approximately 20 percent of Americans say they've taken prescribed drugs for nonmedical reasons. Many take meds that weren't prescribed for them, but instead came from well-intended friends or family.

It's apparent that as a society we've become very comfortable with those little translucent bottles of pills that line our medicine chests. While it might be tempting to "borrow" a little pain reliever that did wonders for your mom's back pain, remember there are hazards to this practice. Drug interactions can be severe and fatal.

Aside from the more benign transgression of sharing meds, in 2008, a study released data on a disturbing trend in which individuals “doctor shop” until they find a physician to prescribe (or re-prescribe) popular pain meds like methadone, hydrocodone and oxycodone. These meds are then illegally distributed. The study highlighted an increase of 550 percent in overdoses due to these drugs in West Virginia, a rural area known for its dependence on prescription drugs.

Professionals like Dr. Adam Bisaga, an associate professor at Columbia University College of Physicians and Surgeons in New York City, support improved guidelines for prescribing along with training to help doctors detect substance abuse disorders in patients to help battle this trend.

How can you minimize your risk for prescription drug misuse?
* Keep a list of all the meds you take, including over-the-counter drugs.
* Never take a medication not prescribed directly for you.
* Make sure your doctor knows about everything you take.
* Take meds as prescribed.
* Read the info provided by the pharmacy about the prescription.
* Ask questions and be sure you understand how to take the drug.
----------------------------------------------------

American Journal of Preventive Medicine Volume 37, Issue 3, Pages 188-194 (September 2009)

Trends in Unintentional Injury Deaths, U.S., 1999--2005: Age, Gender, and Racial/Ethnic Differences

Guoqing Hu, PhDa, Susan P. Baker, MPHbCorresponding Author Informationemail address

published online 13 July 2009.
Background

The details hidden within the recent increase (1999--2004) in unintentional injury mortality have not been studied.
Purpose

The objectives were to analyze the trends in mortality rates from unintentional injuries from 1999 to 2005 and identify changes in rates for specific population subgroups.
Methods

Mortality data came from the CDC's Web-based Injury Statistics Query and Reporting System. Trends during 1999--2005 were analyzed by cause, gender, race, age group, and state separately. Annual percent changes in rates and linear regression were used to measure the increase from 1999 to 2005 and examine its significance. The data were analyzed in 2008.
Results

Overall unintentional injury mortality in the U.S. increased by 1.8/100,000 per year from 1999 to 2005, rising from 35.3/100,000 in 1999 to 39.0 in 2005. Total unintentional injury mortality increased significantly in whites only, a 2% increase per year for white men/boys and a 2.8% increase for white women/girls (p<0.05). Poisoning mortality increased significantly in adults of all racial groups. Subgroup analyses revealed that the increases in total unintentional injury mortality among whites were mainly the result of increases in falls in adults aged ?45 years and poisoning in people aged 15--64 years. Large state-specific differences in trends were observed for these two causes. In addition, the increases in death rates from unintentional suffocation in white children aged <5 years, motor-vehicle crashes in whites aged 45--64 years, and drowning and fire/burns in white women aged 45--54 years were large and significant (p<0.05).
Conclusions

Specific subgroups of whites have recently experienced the most marked increases in fatal unintentional injuries, including falls, poisoning, motor-vehicle crashes, suffocation, fire/burns, and drowning. These increases merit further attention from researchers and policymakers.

a Department of Epidemiology and Health Statistics, School of Public Health, Central South University, Changsha, China

b Center for Injury Research and Policy, Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland

Corresponding Author InformationAddress correspondence and reprint requests to: Susan P. Baker, MPH, Center for Injury Research and Policy, Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, 624 North Broadway, Baltimore MD 21205

PII: S0749-3797(09)00380-8

doi:10.1016/j.amepre.2009.04.023

(c) 2009 American Journal of Preventive Medicine. All rights reserved.


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