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zoom RSS 自閉症の子どもは血液中の水銀濃度が低い

<<   作成日時 : 2009/10/27 20:58   >>

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 多くの親たちは自閉症と水銀の関係について心配している。
 新たな研究によると、自閉症の子どもは正常発達の子どもに比べて血中水銀レベルが低いとわかった。
 水銀濃度は食事に密接に関連し、自閉症関連疾患の子どもは魚を避ける傾向があるという。すでに自閉症と診断された子どもの濃度を測定しているので、新たな発見は、水銀が自閉症の原因となる可能性を否定するものではない。
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Childhood: New Research on Autism and Mercury
http://www.nytimes.com/2009/10/27/health/research/27chil.html
By RONI CARYN RABIN
Published: October 26, 2009

Many parents worry about a possible link between autism and mercury exposure. But most research dismisses those fears as groundless, and a new study says autistic children actually have lower blood levels of mercury than children who are developing normally.

Mercury levels were closely related to fish intake, the study found, and children with autism and related disorders tend to be picky eaters who avoid fish.

After researchers adjusted for the lower fish consumption of autistic children, they found no differences between their mercury levels and those in other children.

Irva Hertz-Picciotto, a professor of public health sciences at the University of California, Davis, who was the study’s principal investigator, said the new findings did not address whether mercury might play a role in autism.

“We were measuring levels after the diagnosis had already been made and was months in the past in most cases,” Dr. Hertz-Picciotto said. “So this study does not provide evidence for or against.”

The report, published online on Oct. 19 in the journal Environmental Health Perspectives, is part of a continuing study comparing autistic and nonautistic children in California. The study of 452 participants includes 249 children with autism or autism spectrum disorders, 143 who are developing normally and 60 with developmental delays.

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FOR IMMEDIATE RELEASE
19 October 2009
http://www.ehponline.org/press/20091019.html
CONTACT: Jenn Betz
919-653-2592

CHARGE Study Shows Comparable Blood Mercury Levels in Children with Autism and Typical Development
Study Analyzes Environmental Factors and Autism


(RESEARCH TRIANGLE PARK, NC) A study published October 19th ahead of print in the peer-reviewed journal Environmental Health Perspectives (EHP) found that 2- to 5-year-old children diagnosed with autism or autism spectrum disorders (AU/ASD) had blood mercury levels similar to those of typically developing control children after adjusting for a variety of sources. The study was conducted through Childhood Autism Risks from Genetics and the Environment (CHARGE), an ongoing study to identify and understand factors contributing to childhood AU/ASD and developmental delays.

Mercury has drawn particular attention in terms of AU/ASD because of its known neurotoxicity. The objective of this study was to compare blood mercury concentrations in typically developing children to concentrations in children with AU/ASD or developmental delay without autism, and to analyze whether differences in mercury sources such as fish consumption explained any differences in blood mercury levels among these groups. The authors also examined dental, medical (including vaccinations) and pharmaceutical sources of mercury exposure.

The authors reported that consumption of tuna, other ocean fish and freshwater fish was the primary predictor of total blood mercury for both typically developing children and those with AU/ASD or developmental delay. Higher blood mercury was also seen in children with amalgam dental fillings who ground their teeth and/or chewed gum.

However, children with AU/ASD were less likely to consume tuna, other ocean fish and freshwater fish, and these children’s blood mercury was significantly reduced compared with that of typically developing controls when differences in fish intake were not accounted for.

This case-control study represents the most rigorous examination to date of differences in circulating blood mercury associated with AU/ASD. However, it did not address whether mercury could be a causative factor in AU/ASD. Analysis of specimens taken before diagnosis will be needed to assess the role of prenatal or early-life mercury exposures in the etiology of autism.

Authors of the paper included Irva Hertz-Picciotto, Peter G. Green, Lora Delwiche, Robin Hansen, Cheryl Walker and Isaac N. Pessah. This work was supported by the National Institutes of Health/National Institute of Environmental Health Sciences, the U.S. Environmental Protection Agency through the Science to Achieve Results (STAR) program and the Medical Investigations of Neurodevelopmental Disorders (MIND) Institute.

The article will be available October 19th free of charge at http://www.ehponline.org/docs/2009/0900736/abstract.html.

EHP is published by the National Institute of Environmental Health Sciences (NIEHS), part of the U.S. Department of Health and Human Services. EHP is an Open Access journal. More information is available online at www.ehponline.org. Brogan & Partners Convergence Marketing handles marketing and public relations for the publication and is responsible for creation and distribution of this press release.

Editor's Note: Working media and other interested parties can register to receive press releases by visiting http://www.ehponline.org/press/, calling 919-653-2592 or e-mailing ehpmedia@brogan.com.

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自閉症の子どもは血液中の水銀濃度が低い 医師の一分/BIGLOBEウェブリブログ
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