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zoom RSS ニンニクが高血圧治療を補助する

<<   作成日時 : 2010/11/17 20:21   >>

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 ニンニクは高血圧の治療薬に加えると有効であるという。オーストラリアのアデレード大の研究によれば、1日ニンニクエキス4カプセル12週間服用で収縮期血圧が対照群と比べて10mmHg低下した。
 ニンニクは心臓によいとされ、コレステロールや高血圧にも良いといわれている。医療目的で数千年前から使用されてきたが、科学的研究が必要とされる。

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つぶした生のニンニクが心臓病に効果大
http://kurie.at.webry.info/200910/article_11.html
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17 November 2010 Last updated at 01:48 GMT
Garlic 'remedy for hypertension'
By Helen Briggs Health reporter, BBC News
http://www.bbc.co.uk/news/health-11767440

画像Garlic may be useful in addition to medication to treat high blood pressure, a study suggests.

Australian doctors enrolled 50 patients in a trial to see if garlic supplements could help those whose blood pressure was high, despite medication.

Those given four capsules of garlic extract a day had lower blood pressure than those on placebo, they report in a scientific journal.

A UK heart charity said more research was needed.

Garlic has long been though to be good for the heart.

Garlic supplements have previously been shown to lower cholesterol and reduce high blood pressure in those with untreated hypertension.

In the latest study, researchers from the University of Adelaide, Australia, looked at the effects of four capsules a day of a supplement known as aged garlic for 12 weeks.

They found systolic blood pressure was around 10mmHg lower in the group given garlic compared with those given a placebo.

Researcher Karin Ried said: "Garlic supplements have been associated with a blood pressure lowering effect of clinical significance in patients with untreated hypertension.

"Our trial, however, is the first to assess the effect, tolerability and acceptability of aged garlic extract as an additional treatment to existing antihypertensive medication in patients with treated, but uncontrolled, hypertension."

Experts say garlic supplements should only be used after seeking medical advice, as garlic can thin the blood or interact with some medicines.

Ellen Mason, senior cardiac nurse at the British Heart Foundation, said using garlic for medicinal purposes dates back thousands of years, but it is essential that scientific research proves that garlic can help conditions such as raised blood pressure.

She said: "This study demonstrated a slight blood pressure reduction after using aged garlic supplements but it's not significant enough or in a large enough group of people to currently recommend it instead of medication.

"It's a concern that so many people in the UK have poorly controlled blood pressure, with an increased risk of stroke and heart disease as a consequence. So enjoy garlic as part of your diet but don't stop taking your blood pressure medication."

The study is reported in the journal Maturitas.

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doi:10.1016/j.maturitas.2010.06.001 | How to Cite or Link Using DOI
Copyright (c) 2010 Elsevier Ireland Ltd All rights reserved.

Aged garlic extract lowers blood pressure in patients with treated but uncontrolled hypertension: A randomised controlled trial
Alert
This article is not included in your organization's subscription. However, you may be able to access this article under your organization's agreement with Elsevier.

Karin RiedCorresponding Author Contact Information, a, E-mail The Corresponding Author, Oliver R. Franka, E-mail The Corresponding Author and Nigel P. Stocksa, E-mail The Corresponding Author

a Discipline of General Practice, School of Population Health and Clinical Practice, The University of Adelaide, Adelaide, South Australia 5005, Australia
Received 14 April 2010;
revised 18 May 2010;
accepted 2 June 2010.
Available online 1 July 2010.

Abstract
Objective

To assess the effect, tolerability and acceptability of aged previous termgarlicnext term extract as an adjunct treatment to existing antihypertensive medication in patients with treated, but uncontrolled, hypertension.
Design

A double-blind parallel randomised placebo-controlled trial involving 50 patients whose routine clinical records in general practice documented treated but uncontrolled hypertension. The active treatment group received four capsules of aged previous termgarlicnext term extract (960 mg containing 2.4 mg S-allylcysteine) daily for 12 weeks, and the control group received matching placebos. The primary outcome measures were systolic and diastolic blood pressure at baseline, 4, 8 and 12 weeks, and change over time. We also assessed tolerability during the trial and acceptability at 12 weeks.
Results

In patients with uncontrolled hypertension (SBP ? 140 mm Hg at baseline), systolic blood pressure was on average 10.2 ± 4.3 mm Hg (p = 0.03) lower in the previous termgarlicnext term group compared with controls over the 12-week treatment period. Changes in blood pressure between the groups were not significant in patients with SBP < 140 mm Hg at baseline. Aged previous termgarlicnext term extract was generally well tolerated and acceptability of trial treatment was high (92%).
Conclusion

Our trial suggests that aged previous termgarlicnext term extract is superior to placebo in lowering systolic blood pressure similarly to current first line medications in patients with treated but uncontrolled hypertension.

Keywords: Cardiovascular health; Uncontrolled hypertension; Aged previous termgarlicnext term extract; Complementary medicine


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