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<<   作成日時 : 2012/03/15 20:20   >>

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食事と精子数低下が関連
 飽和脂肪の多い食事と精子数の減少が関連。ジャンクフード食事をとる人で精子の質の低下が見られた。脂肪を一番多くとった人は精子数が43%低く、精子濃度は38%低かった。魚や植物油にあるオメガ3脂肪酸の摂取量が多いことがより高い精子濃度と関連していた。

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14 March 2012 Last updated at 07:39 GMT
Diet 'linked' to low sperm counts
http://www.bbc.co.uk/news/health-17353804

画像A diet high in saturated fat has been linked with a reduced sperm count.

A study of 99 men attending a US fertility clinic found those eating junk food diets had poorer sperm quality.

High intakes of omega-3 fatty acids, found in fish and plant oils, were associated with higher sperm concentration.

More work is needed to confirm the findings, the researchers report in the journal Human Reproduction.

The team, led by Prof Jill Attaman from Harvard Medical School in Boston, questioned men about their diet and analysed sperm samples over the course of four years.

Compared with those eating the least fat, men with the highest fat intake had a 43% lower sperm count and 38% lower sperm concentration (number of sperm per unit volume of semen).

Continue reading the main story

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..it does add weight to the argument that having a good healthy diet may benefit male fertility as well as being good general health advice.”

Dr Allan Pacey
University of Sheffield
Men consuming the most omega-3 fatty acids had sperm with a more normal structure than men with the lowest intake.

Prof Attaman said: "The magnitude of the association is quite dramatic and provides further support for the health efforts to limit consumption of saturated fat given their relation with other health outcomes such as cardiovascular disease."

However, 71% of participants were overweight or obese, which could have had an impact on sperm quality. Furthermore, none of the men had sperm counts or concentrations below the "normal" levels defined by the World Health Organization of at least 39 million and 15 million per millilitre.

Commenting on the research, British fertility expert Dr Allan Pacey, of the University of Sheffield, said: "This is a relatively small study showing an association between dietary intake of saturated fats and semen quality.

"Perhaps unsurprisingly there appeared to be a reasonable association between the two, with men who ate the highest levels of saturated fats having the lowest sperm counts and those eating the most omega-3 polyunsaturated fats having the highest.

"Importantly, the study does not show that one causes the other and further work needs to be carried out to clarify this. But it does add weight to the argument that having a good healthy diet may benefit male fertility as well as being good general health advice."

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Dietary fat and semen quality among men attending a fertility clinic

Jill A. Attaman1,*, Thomas L. Toth1, Jeremy Furtado2, Hannia Campos2, Russ Hauser1,3 and Jorge. E. Chavarro2,4
+ Author Affiliations

1Vincent Obstetrics and Gynecology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02115, USA
2Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
3Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
4Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA
?*Correspondence address. Tel: +1-603-653-9240; Fax: +1-603-650-0906; E-mail: Jill.A.Attaman@hitchcock.org
Received June 30, 2011.
Revision received December 7, 2011.
Accepted December 21, 2011.
Abstract

BACKGROUND The objective of this study was to examine the relation between dietary fats and semen quality parameters.

METHODS Data from 99 men with complete dietary and semen quality data were analyzed. Fatty acid levels in sperm and seminal plasma were measured using gas chromatography in a subgroup of men (n = 23). Linear regression was used to determine associations while adjusting for potential confounders.

RESULTS Men were primarily Caucasian (89%) with a mean (SD) age of 36.4 (5.3) years; 71% were overweight or obese; and 67% were never smokers. Higher total fat intake was negatively related to total sperm count and concentration. Men in the highest third of total fat intake had 43% (95% confidence interval (CI): 62?14%) lower total sperm count and 38% (95% CI: 58?10%) lower sperm concentration than men in the lowest third (Ptrend = 0.01). This association was driven by intake of saturated fats. Levels of saturated fatty acids in sperm were also negatively related to sperm concentration (r= ?0.53), but saturated fat intake was unrelated to sperm levels (r = 0.09). Higher intake of omega-3 polyunsaturated fats was related to a more favorable sperm morphology. Men in the highest third of omega-3 fatty acids had 1.9% (0.4?3.5%) higher normal morphology than men in the lowest third (Ptrend = 0.02).

CONCLUSIONS In this preliminary cross-sectional study, high intake of saturated fats was negatively related to sperm concentration whereas higher intake of omega-3 fats was positively related to sperm morphology. Further, studies with larger samples are now required to confirm these findings.

Key words
male infertility semen quality diet fat gas chromatography

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