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<<   作成日時 : 2012/08/30 20:06   >>

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チョコレートで脳卒中を予防する
画像 37,000人以上のスウェーデン男性の研究によれば、チョコレートをたくさん食べると脳卒中を予防する可能性があるという。
 1週間に食べるチョコレートの量で4群に分けると、最下位グループは摂取がゼロで、最上位は63gで、比較すると最上位群は脳卒中の発症が17%低かった。成分のフラボノイドは、抗酸化作用、抗凝固、抗炎症作用を介して心血管系に保護的に作用しており、悪玉コレステロールを下げ、血圧を下げる可能性がある。
 しかしながら、適度な運動や健康的な食事に代わるものとして推奨すべきではない。チョコレートの砂糖や脂肪にも注意が必要である。

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29 August 2012 Last updated at 20:41 GMT
Chocolate may protect the brain from stroke
http://www.bbc.co.uk/news/health-19402143

Chocolate might not be the healthiest thing for your waistline - but research suggests it may protect against stroke.

A study following more than 37,000 Swedish men showed those eating the most chocolate were the least likely to have a stroke.

It follows on from other studies that have suggested eating chocolate can improve the health of the heart.

However, researchers and the Stroke Association warned the findings were not an excuse to overeat chocolate.

Everyone taking part in the study was asked about their eating habits and their health was monitored for a decade.

They were split into four groups based on the amount of chocolate, with the bottom group eating, on average, no chocolate each week and the top group having 63g (2.2oz) - slightly more than an average bar.

Comparing the top and bottom groups showed those eating the most chocolate were 17% less likely to have a stroke during the study, published in the journal Neurology.

Flavonoids
One of the researchers, Prof Susanna Larsson, from the Karolinska Institute in Sweden, said: "The beneficial effect of chocolate consumption on stroke may be related to the flavonoids in chocolate.

"Flavonoids appear to be protective against cardiovascular disease through antioxidant, anti-clotting and anti-inflammatory properties.

"It's also possible that flavonoids in chocolate may decrease blood concentrations of bad cholesterol and reduce blood pressure."

The study also noted that while dark chocolate had been linked to benefits for the heart in the past, milk chocolate was the preferred option in Sweden and in the study.

Dr Clare Walton, from the Stroke Association, said: "Past research has shown that eating dark chocolate might go some way to reducing your stroke risk if it is eaten as part of a healthy, balanced diet.

"This study suggests that eating a moderate amount of other types of chocolate could also be beneficial in men.

"However, a lot more research is needed and these results should not be used as an excuse for men to eat chocolate as an alternative to regular exercise or eating a healthy diet to reduce their risk of stroke."

The authors of the study warned of the high sugar and fat content of chocolate.

"It should be consumed in moderation," they said.



----------------------------------------------------
Neurology WNL.0b013e31826aacfa; published ahead of print August 29, 2012,

Chocolate consumption and risk of stroke
A prospective cohort of men and meta-analysis


Susanna C. Larsson, PhD, Jarmo Virtamo, MD and Alicja Wolk, DMSc

From the Division of Nutritional Epidemiology (S.C.L., A.W.), Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; and Department of Chronic Disease Prevention (J.V.), National Institute for Health and Welfare, Helsinki, Finland.
Correspondence & reprint requests to Dr. Larsson: susanna.larsson@ki.se
View Complete Disclosures

ABSTRACT

Objective: To investigate the association between chocolate consumption and risk of stroke in men and conduct a meta-analysis to summarize available evidence from prospective studies of chocolate consumption and stroke.

Methods: We prospectively followed 37,103 men in the Cohort of Swedish Men. Chocolate consumption was assessed at baseline using a food-frequency questionnaire. Cases of first stroke were ascertained from the Swedish Hospital Discharge Registry. For the meta-analysis, pertinent studies were identified by searching the PubMed and EMBASE databases through January 13, 2012. Study-specific results were combined using a random-effects model.

Results: During 10.2 years of follow-up, we ascertained 1,995 incident stroke cases, including 1,511 cerebral infarctions, 321 hemorrhagic strokes, and 163 unspecified strokes. High chocolate consumption was associated with a lower risk of stroke. The multivariable relative risk of stroke comparing the highest quartile of chocolate consumption (median 62.9 g/week) with the lowest quartile (median 0 g/week) was 0.83 (95% CI 0.70?0.99). The association did not differ by stroke subtypes. In a meta-analysis of 5 studies, with a total of 4,260 stroke cases, the overall relative risk of stroke for the highest vs lowest category of chocolate consumption was 0.81 (95% CI 0.73?0.90), without heterogeneity among studies (p = 0.47).

Conclusion: These findings suggest that moderate chocolate consumption may lower the risk of stroke.

Received February 2, 2012.
Accepted May 1, 2012.
Copyright c 2012 by AAN Enterprises, Inc.

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